Akitada Ichinose Selected Research

Factor XIII (Coagulation Factor XIII)

1/2022	First and fatal case of autoimmune acquired factor XIII/13 deficiency after COVID-19/SARS-CoV-2 vaccination.
5/2021	Pathological coagulation parameters in as many as 54 patients with autoimmune acquired factor XIII deficiency due to anti-factor XIII autoantibodies.
1/2021	Important roles of the human leukocyte antigen class I and II molecules and their associated genes in the autoimmune coagulation factor XIII deficiency via whole-exome sequencing analysis.
1/2017	Successful Management of a Patient with Autoimmune Hemorrhaphilia due to Anti-Factor XIII/13 Antibodies Complicated by Pulmonary Thromboembolism.
1/2017	Autoimmune acquired factor XIII deficiency due to anti-factor XIII/13 antibodies: A summary of 93 patients.
5/2016	Erratum to: Successful bypass surgery for esophageal carcinoma under adequate factor XIII/13 replacement therapy in a case of intractable autoimmune hemorrhaphilia due to anti-Factor XIII/13 antibodies.
4/2016	Non-autoimmune combined factor XIII A and B subunit deficiencies in rheumatoid arthritis patients treated with anti-interleukin-6 receptor monoclonal antibody (tocilizumab).
3/2016	Successful bypass surgery for esophageal carcinoma under adequate factor XIII/13 replacement therapy in a case of intractable autoimmune hemorrhaphilia due to anti-Factor XIII/13 antibodies.
6/2015	Report of a patient with chronic intractable autoimmune hemorrhaphilia due to anti-factor XIII/13 antibodies who died of hemorrhage after sustained clinical remission for 3 years.
6/2015	Rapid immunochromatographic test for detection of anti-factor XIII A subunit antibodies can diagnose 90 % of cases with autoimmune haemorrhaphilia XIII/13.

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Akitada Ichinose Research Topics

Disease

35	Hemorrhage 11/2022 - 08/2005
10	Hemophilia A (Haemophilia) 01/2022 - 04/2013
9	Factor XIII Deficiency 05/2022 - 12/2010
8	Thrombosis (Thrombus) 01/2020 - 11/2008
3	Inflammation (Inflammations) 05/2022 - 04/2012
2	Confusion (Bewilderment) 01/2022 - 06/2015
2	Infections 01/2020 - 01/2017
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2020 - 09/2013
2	Type I Plasminogen Deficiency 08/2016 - 06/2009
2	Carcinoma (Carcinomatosis) 05/2016 - 03/2016
2	Renal Cell Carcinoma (Grawitz Tumor) 04/2016 - 09/2013
2	Rheumatoid Arthritis 04/2016 - 12/2012
2	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 04/2016 - 07/2015
2	Neoplasms (Cancer) 04/2016 - 11/2015
2	Thrombocytopenia (Thrombopenia) 07/2015 - 11/2014
2	Disseminated Intravascular Coagulation 11/2014 - 09/2013
2	Spontaneous Abortion (Miscarriage) 08/2005 - 12/2003
1	COVID-19 01/2022
1	Hemorrhagic Disorders (Hemorrhagic Diathesis) 01/2022
1	Immunoglobulin Light-chain Amyloidosis 04/2020
1	Factor V Deficiency 01/2020
1	Wound Infection (Wound Infections) 01/2020
1	Femoral Fractures (Femoral Fracture) 01/2020
1	Diabetes Mellitus 02/2019
1	Necrosis 02/2019
1	Myocardial Infarction 01/2019
1	Anemia 01/2019
1	Factor X Deficiency 01/2019
1	Hematoma 10/2017
1	Acute Subdural Hematoma 10/2017
1	Hemostatic Disorders 01/2017
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2017
1	Neutropenia 01/2017
1	Pulmonary Embolism 01/2017
1	Mucositis 08/2016
1	Purpura 04/2016
1	Esophageal Neoplasms (Esophageal Cancer) 04/2016
1	Autoimmune Diseases (Autoimmune Disease) 07/2015
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2015
1	Disease Susceptibility (Diathesis) 07/2015
1	Cardiac Tamponade 06/2015
1	Aortic Aneurysm (Aneurysm, Aortic) 11/2014
1	Abdominal Aortic Aneurysm 09/2013

Drug/Important Bio-Agent (IBA)

18	AutoantibodiesIBA 05/2022 - 04/2013
17	Factor XIII (Coagulation Factor XIII)IBA 01/2022 - 12/2003
10	AntibodiesIBA 03/2022 - 01/2012
5	Blood Coagulation Factors (Coagulation Factor)IBA 05/2022 - 07/2014
4	Factor V (Coagulation Factor V)IBA 03/2022 - 01/2019
4	Hemostatics (Antihemorrhagics)IBA 03/2022 - 06/2015
3	Factor X (Stuart Factor)IBA 03/2022 - 01/2019
3	Factor VIII (Coagulation Factor VIII)IBA 04/2020 - 04/2016
3	Prednisolone (Predate)FDA LinkGeneric 01/2017 - 10/2015
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017 - 06/2015
2	AnticoagulantsIBA 01/2020 - 07/2014
2	Rituximab (Mabthera)FDA Link 01/2017 - 06/2015
2	Fibrinolysin FDA Link 08/2016 - 11/2003
2	tocilizumab (atlizumab)FDA Link 04/2016 - 12/2012
2	Inosine Triphosphate (ITP)IBA 04/2016 - 07/2015
2	Dacarbazine (DIC)FDA LinkGeneric 11/2014 - 09/2013
2	AntithrombinsIBA 07/2014 - 06/2009
2	plasma protein Z (protein Z)IBA 03/2012 - 01/2005
1	von Willebrand FactorIBA 11/2022
1	ProteomeIBA 05/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	CTLA-4 AntigenIBA 01/2021
1	Tranexamic Acid (AMCA)FDA Link 04/2020
1	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 04/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	Factor VIIa (Activated Factor VII)IBA 09/2019
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2019
1	SteroidsIBA 01/2017
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2017
1	estropipate (Ogen)FDA LinkGeneric 08/2016
1	Pancreatic Elastase (Elastase)IBA 08/2016
1	PlasminogenIBA 08/2016
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 04/2016
1	Monoclonal AntibodiesIBA 04/2016
1	Prednisone (Sone)FDA LinkGeneric 07/2015
1	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2015
1	Thrombin FDA Link 05/2015
1	Factor XIIIaIBA 05/2015
1	Enzyme Precursors (Zymogens)IBA 05/2015
1	FibrinIBA 05/2015
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2015
1	ThrombomodulinIBA 11/2014
1	Protein CIBA 07/2014
1	Protein SIBA 07/2014

Therapy/Procedure

11	Therapeutics 02/2019 - 08/2005
2	Renal Dialysis (Hemodialysis) 01/2020 - 02/2019
2	Plasma Exchange 08/2018 - 01/2013
1	Debridement 01/2020
1	Replacement Arthroplasty 01/2020
1	Thrombectomy 02/2019
1	Thrombolytic Therapy 02/2019
1	Punctures 02/2019
1	Platelet Transfusion (Blood Platelet Transfusions) 08/2018
1	Craniotomy 10/2017
1	Radiotherapy 04/2016
1	Nephrectomy 04/2016
1	Hysterectomy 11/2015